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Signosis Luciferease Reporter Stable Cell Lines 2017-04-27 16:06:26

 
 

Gene function analysis, target discovery and validation, assay development, and compound screening often need cell-based assays.  Stable cell lines that are engineered to express a gene of interest via transgene integrations into the host genome provide an efficient approach to conduct such analysis.  At Signosis, we help researchers save time and labor in generating and validating stable cell lines so scientists can spend more effort on solving the big questions.  We offer a wide-selection of validated luciferase reporter cell lines that measure transcription factor activity as a read-out for various signaling pathways.

 
[특징]

Routine mycoplasma testing - All cell lines tested negative for mycoplasma.

High sensitive and responsive - Each cell line is validated to induce strong reporter signal in response to stimuli.

Consistent - TF reporter construct is stably integrated into the genome to avoid experimental/cell-to-cell variations.

Time saving - Cell line can be used for experiments right away to study different signaling pathways.

Firefly Luciferase Substrate
 
[제품 List]

 
Transcription Factors
Pathway
Cell Line
Academic
 Industry
NFkB
NFkB

Hela; human cervical cancer

SL-0001-NP
SL-0001-FP
NFkB
NFkB

NIH/3T3; mouse fibroblast

SL-0006-NP
SL-0006-FP
NFkB
NFkB

HEK293; human embryonic kidney

SL-0012-NP
SL-0012-FP
NFkB 
NFkB

MCF-7; human breast cancer

SL-0013-NP
SL-0013-FP
NFkB
NFkB

A549; human lung cancer

SL-0014-NP
SL-0014-FP
NFkB
NFkB

HepG2; human liver cancer

SL-0017-NP
SL-0017-FP
NFkB
NFkB

Neuro2a; mouse neuroblastoma

SL-0026-NP
SL-0026-FP
NFkB
NFKB

MDA-MB-231, Human brest cancer

SL-0043-NP
SL-0043-FP
NFkB
NFkB

MEF; murine embryonic fibroblast

SL-0033-NP
SL-0033-FP
NFKB
NFKB

Jurkat T; Human T Lymphocyte

SL-0050-NP
SL-0050-FP
NFAT  
Calcium Signaling

Jurkat T; human T lymphocyte

SL-0032-NP
SL-0032-FP
NFAT
Calcium Signaling

Hela; human cervical cancer

SL-0018-NP
SL-0018-FP
NFAT
Calcium Signaling

NIH/3T3; mouse fibroblast

SL-0029-NP
SL-0029-FP    
p53
p53

Hela; human cervical cancer

SL-0011-NP
SL-0011-FP
p53
p53

RKO; human colon cancer

SL-0007-NP
SL-0007-FP
SMAD 2/3
TGFbeta pathway

HepG2; human liver cancer

SL-0016-NP
SL-0016-FP
SMAD 2/3
TGFbeta pathway

NIH/3T3; mouse fibroblast

SL-0030-NP
SL-0030-FP
SMAD 1/5/8
BMP pathway

HEK293; human embyronic kidney

SL-0051-NP
SL-0051-FP
NRF2/ARE

Antioxidant Response

HEK293;Human embyronic kidney

SL-0042-NP
SL-0042-FP
NRF2/ARE

Antioxidant Response

NIH3T3;Mouse fibroblast

SL-0047-NP
SL-0047-FP
NRF2/ARE

Antioxidant response

HepG2; Human Liver cancer

SL-0046-NP
SL-0046-FP
NRF2/ARE

Antioxidant Response

MCF7; human breast cancer

SL-0010-NP
academic only
STAT1
JAK-STAT

Hela; human cervical cancer

SL-0004-NP
SL-0004-FP
STAT3
JAK-STAT

Hela; human cervical cancer

SL-0003-NP
SL-0003-FP
HIF
Hypoxia Response

NIH/3T3; mouse fibroblast

SL-0005-NP
SL-0005-FP
HIF
Hypoxia Response

Hela; human cervical cancer

SL-0023-NP
SL-0023-FP
HIF
Hypoxia Response

Neuro2a; mouse neuroblastoma

SL-0027-NP
SL-0027-FP
HIF
Hypoxia Response

Cos-7; Monkey  fibroblast

SL-0034-NP
SL-0034-FP
ER

Estrogen Receptor Signaling

T47D; human breast cancer

SL-0002-NP
SL-0002-FP
AR

Androgen Receptor Signaling

MDA-MB-453; human breast cancer

SL-0008-NP
SL-0008-FP
 GR
Glucocorticoid Receptor Signaling

MDA-MB-453; human breast cancer

SL-0009-NP
SL-0009-FP
GR
Glucocorticoid Receptor Signaling

Hela; human cervical cancer

SL-0021-NP
SL-0021-FP
AP-1
JNK, ERK, MAPK Signaling

Hela; human cervical cancer

SL-0019-NP
SL-0019-FP
CREB

cAMP, PKA, CaMK Signaling

HEK293; human embryonic kidney

SL-0020-NP
SL-0020-FP
CREB

cAMP, PKA, CaMK Signaling

NIH/3T3; mouse fibroblast

SL-0031-NP
SL-0031-FP
CHOP
Unfolded Protein Response, ER stress

Mia-Paca2; human pancreatic cancer

SL-0025-NP
SL-0025-FP
TCF/LEF
Wnt/b-catenin

HEK293; human embryonic kidney

SL-0015-NP
SL-0015-FP
TCF/LEF
Wnt/b-catenin

Hela; human cervical cancer

SL-0022-NP
SL-0022-FP
TCF/LEF
Wnt/b-catenin

CHO-K1;Chinese Hamster Ovary

SL-0028-NP
SL-0028-FP
ELK
MAPK Signaling

HEK293; human embyronic kidney

SL-0040-NP
SL-0040-FP
ELK
MAPK Signaling

Hela; human cervical cancer

SL-0041-NP
SL-0041-FP
IRF

Immune Response Pathway

HEK293; human embyronic kidney

SL-0035-NP
SL-0035-FP
IRF

Immune Response Pathway

HePG2;Human Liver Cancer

SL-0049-NP
SL-0049-FP
ATF6
Unfolded Protein Response, ER stress

CHO-K1;Chinese Hamster Ovary

SL-0024-NP
SL-0024-FP
IL-6
MAPKs, PI3Ks, STATs Signaling

HEK293; human embryonic kidney

SL-0048-NP
SL-0048-FP
IFN-α/ISRE

TYK2 and JAK1 Signaling

HeLa; human cervical cancer

SL-0052-NP
SL-0052-FP
MRF
Metal Pathway

HEK293; human embryonic Kidney

SL-0053-NP
SL-0053-FP
Control
 

Hela; human cervical cancer

SL-0038
 
Control 
 

HepG2; human liver cancer

SL-0039
 
 
 
                                                         
  
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