주요상품

Biocare Medical Skin Cancer Awareness Month 2015-05-12 09:10:58


바이오케어3.jpg

 

Skin Cancer Awareness Month

Antibodies to Aid in the Fight Against Skin Cancer

 

Tonsil stained with CD4 (M) + CD8 (RM)

CD4 (M) + CD8 (RM)

The expression or loss of both CD4 and CD8 is more likely in mycosis fungoides-type cutaneous T-cell lymphomas than reactive T-cell infiltrates. A CD4:CD8 ratio greater than 2 may also be helpful in distinguishing mycosis fungoides from its inflammatory mimics.

Melanoma stained with Pan Melanoma (FR) + Ki-67 (DAB) cocktail

Pan Melanoma +
Ki-67

Pan Melanoma (MART-1 + Tyrosinase) + Ki-67 aids to identify the proliferation rate of melanocytic lesions in cases with sparse melanocytes, dense lymphocytic infiltrates or melanocytes mixed with fibroblasts. In general, a higher proliferative fraction is seen in melanoma than in melanocytic nevi.

Melanoma stained with Pan Melanoma + S100 antibody

Pan Melanoma +
S100

Pan Melanoma (MART-1 + Tyrosinase) + S100 may aid in identifying metastatic melanoma. MART-1 is specific for melanocytic lesions while tyrosinase is a sensitive marker labeling a high percentage of desmoplastic melanomas. S100 stains almost all benign and malignant melanomas and their metastases.

Learn More

Learn More

Learn More

 

Melanoma stained with HMB45 + MART-1 + Tyrosinase Antibody

HMB45 + MART-1 + Tyrosinase

HMB45 + MART-1 + Tyrosinase is an antibody cocktail suitable as a pan melanoma screener. HMB45 is relatively specific for melanomas. MART-1/Melan A is specific to melanocytic lesions and labels metastatic melanomas. Tyrosinase labels a high percentage of desmoplastic melanomas.

Metastatic melanoma stained with Microphthalmia Transcription Factor Antibody

Microphthalmia Transcription Factor

Microphthalmia Transcription Factor (MiTF) is a sensitive and specific marker for malignant melanoma, including some spindle-cell variants. MiTF may be useful for identification of melanoma, melanocytic soft tissue tumors and the perivascular epithelioid cell family of tumors (PEComas).

Neurotrophic melanoma stained with Nerve Growth Factor Receptor Antibody

Nerve Growth Factor Receptor

Nerve Growth Factor Receptor (NGFR), along with S100, may diagnose desmoplastic and neurotrophic malignant melanomas, which are often negative for other melanocytic markers (HMB45, MART-1/Melan-A). Also known as p75, it is expressed on Schwann cells, neuronal axons and perineural cells.

Learn More

Learn More

Learn More

 

pHH3 (RM) Staining Melanoma

pHH3 (RM)

Phosphohistone H3 (pHH3) (RM) is a sensitive marker specific for cells undergoing mitosis. IHC with pHH3 may provide a more accurate assessment of all mitotic cells compared to H&E. Prognostic significance of the mitotic index has been reported to be of great value in melanoma.

(Left) Spindle cell melanoma (DAB); (Right) Pigmented melanoma (Fast red)

SOX10 (M)

SOX10 is an important marker in melanoma, gliomas and benign tumors such as schwannomas. It is expressed in 97-100% of desmoplastic and spindle cell melanomas and in 100% of nevi. The majority of oligodendrogliomas, astrocytomas, and poorly differentiated glioblastomas also express SOX10.

Cutaneous melanoma stained with Vimentin antibody

Vimentin

Vimentin may be useful as an epithelial-mesenchymal transition marker, giving an indication of tumor progression and potential for metastasis. It tends to be expressed in atypical fibroxanthomas, desmoplastic melanomas and leiomyosarcomas but not in most spindle cell squamous cell carcinomas.

Learn More

Learn More

Learn More



바이오케어4.jpg

안티바디.PNG
목록보기
최근본상품 TOP